CORNEA CARE
Descemet's Membrane Endothelial Keratoplasty – DMEK
DMEK selectively replaces Descemet's membrane and the endothelial pump-cell layer without donor stroma. It is used for suitable endothelial disease when the front cornea is otherwise healthy. Because the graft is extremely thin, surgery and early positioning require precise technique and close follow-up.
DMEK most closely replaces the diseased anatomical layers in endothelial failure. With no donor stroma added, it can offer strong visual potential and a low rejection risk in suitable eyes. The technique is not automatically appropriate for every patient; significant anterior scarring, complex internal anatomy or previous surgery can make another approach safer.
The transparent graft naturally rolls with the endothelial cells facing outward. During surgery it must be correctly oriented, unfolded and centred without excessive handling. An air or gas bubble then supports attachment. Vision can remain hazy while swelling clears, and a partially detached graft may need rebubbling. Follow-up also checks pressure and steroid response.
1. Who may be suitable for DMEK?
Fuchs endothelial corneal dystrophy causing swelling or reduced vision
Selected cases of endothelial failure after cataract or other eye surgery
Eyes with a relatively clear anterior cornea and anatomy suitable for graft unfolding
2. The DMEK procedure
Pre-operative assessment
Corneal clarity, thickness, eye pressure, lens status and previous surgery are reviewed before planning.
Replace diseased cells
The surgeon removes the faulty inner membrane, inserts the rolled donor graft and carefully unfolds it.
Bubble attachment
Air or gas holds the tissue against the back of the cornea while the cells begin restoring fluid balance.
3. Potential benefits and practical limits
Anatomical replacement
Only the layers responsible for endothelial pumping are transplanted.
Visual potential
Suitable eyes may achieve good optical quality because no donor stromal layer is added.
Technically demanding
Very thin tissue can detach or be difficult to position, and some eyes are better served by DSEK.
4. Aftercare and risks
- Face-up positioning may be advised and air travel must be avoided while a gas bubble remains
- Rebubbling, rejection, graft failure, pressure rise, infection or retinal complications can occur
- Prescribed steroid drops and regular checks help protect graft function
Why choose Perfect Vision Laser Eye Hospital, Jaipur?
- Led by Dr. Virendra Agrawal, MD (Ophthalmology), AIIMS New Delhi, with a full-time specialist team
- Diagnosis-first approach with advanced imaging before any recommendation
- Comprehensive eye services available at one Jaipur centre
- Support for patients travelling from across Rajasthan and outside the state
- Cashless Mediclaim assistance, subject to your policy terms
Your specialists
Dr. Neha Pathak
Consultant Cornea Specialist. MBBS, MS (Ophthalmology) — Fellowship in Cornea & General Ophthalmology, Aravind Eye Hospital, Madurai · Experience: 11+ Years of Ophthalmology
Surgical excellence, patient safety, evidence-based decision-making and personalised care — with an emphasis on choosing the right treatment for every individual patient.
Dr. Amit Mishra
Senior Consultant — Cataract, Refractive & Glaucoma. MBBS, MS (Ophthalmology) · Experience: 25+ Years of Ophthalmology
Advanced eye care is a balance of proven surgical technique and ongoing learning. Every patient deserves a careful evaluation, a clear explanation of options and a treatment plan built around their individual vision and eye health.
Dr. Virendra Agrawal
Medical Director & Chief Consultant — Cataract & Refractive Surgery. MD (Ophthalmology), DNB, MNAMS, FAICO (Cataract & Refractive Surgery) — Bodh Raj Sabarwal Gold Medalist (AIIMS, New Delhi) · Experience: 30+ Years of Ophthalmology
Every eye is different. The right procedure is the one that fits your cornea, your lens, your retina and the way you use your vision every day — not the one that is most advertised. Technology supports the decision; it never replaces the clinical evaluation.
Patient reviews from Google
Verified public Google reviews for Perfect Vision Laser Eye Hospital – Dr. Virendra Laser Phaco Surgery Centre, Jaipur. Reviews are individual patient opinions and are not a guarantee of similar results.
“Dr Virendra is absolutely amazing and makes you feel really comfortable. I have visited the centre several times for lens fitting after getting my keratoconus treated by Dr Anita Agarwal, and every time the entire staff was really supportive to get me the perfect RGO le s after keratoconus. Thanks to Dr saab and mam for all the efforts.”
“Best eye hospital in jaipur . Came for Keratoconus treatment and consulted with Dr Neha Pathak the cornea specialist who was very helpful. I got C3R operation done and I am satisfied with the results and professional behaviour of the staff”
“The staff here is absolutely amazing. I had my keratoconus treatment from here and i am very satisfied with it. Now, I am very used toh these great lenses also,I would surely recommend you to visit if you have any problem related to eyes.”
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Descemet's Membrane Endothelial Keratoplasty – DMEK — Jaipur FAQs
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Arrange a DMEK consultation and complete corneal evaluation in Jaipur.